![]() ![]() ![]() Published by Oxford University Press on behalf of the Sleep Research Society. Symptoms of Narcolepsy can include excessive daytime sleepiness (EDS), sleep disruption, cataplexy, sleep paralysis and hypnagogic/hypnopompic hallucinations. H1N1 Pandemrix narcolepsy type 1 narcolepsy with cataplexy psychiatric symptoms. Fragmented sleep was significantly associated with psychiatric symptoms. We found a high prevalence of psychiatric symptoms in NC1 patients. Hypocretin-1 levels showed no association with psychiatric symptoms. In adults, awakening index, but not sleep-stage shift index, was positively associated with internalizing score (p = 0.015). Narcolepsy affects an equal number of boys and girls. However, in children fragmented sleep, measured by sleep-stage shift index was significantly negatively associated with all the psychiatric summary scores (all p ≤ 0.020), and awakening index was negatively associated with externalizing (p = 0.042) and total summary scores (p = 0.042). There are 2 types: Type 1: Narcolepsy due to hypocretin deficiency and accompanied by cataplexy (momentary muscular weakness or paralysis evoked by sudden emotional reactions) Type 2: Narcolepsy with normal hypocretin levels and without cataplexy The Kleine-Levin syndrome, a very rare disorder in adolescent boys, resembles narcolepsy. Psychiatric symptoms and excessive daytime sleepiness were not associated. However, 27.5% of children and 22.2% of adults still remained within the total psychiatric symptoms clinical range. Narcolepsy type 1, previously called narcolepsy with. T-scores were lower when the questionnaire's sleep-related items were excluded. Narcolepsy has two forms in both children and adults, depending on whether cataplexy is present 1. Internalizing symptom T-scores showed that 37.5% of the children and 33.3% of the adults were in the clinical range of concern. ![]() The mean (SD) total T-scores were 58.6 (9.2) for children and 57.0 (9.8) for adults, these being mainly driven by internalizing problems. Psychiatric symptoms were assessed by the Achenbach System of Empirically Based Assessment (ASEBA) Child Behavior Check List (CBCL) in children and by Adult Self Report (ASR) in adults. We also wanted to explore possible causes of the psychiatric symptoms seen in NC1.Ĭross-sectional study. The primary aim of this study was to explore the extent of psychiatric symptoms in a cohort of Norwegian NC1 patients, most of whom were H1N1-vaccinated. Several studies have reported psychiatric comorbidity in patients with narcolepsy type 1 (NC1). ![]()
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